U.S. Food and Drug Administration (FDA)

The U.S. Food and Drug Administration (FDA) is the primary regulatory body in the United States responsible for ensuring the safety, efficacy, and quality of medical products. FDA certification means that the product has undergone comprehensive testing and meets the highest safety and effectiveness standards.

We are proud to announce

that our Piguiay® GLP-1 Nano Microneedle Patch is now FDA certified! 

Our product has officially passed the FDA’s strict regulatory review, which includes in-depth scientific evaluation, clinical validation, and quality assurance testing. This confirms that the Piguiay® 𝗚𝗟𝗣-𝟭 𝗡𝗮𝗻𝗼 𝗠𝗶𝗰𝗿𝗼𝗻𝗲𝗲𝗱𝗹𝗲 𝗣𝗮𝘁𝗰𝗵 is a safe, effective, and non-invasive solution for supporting weight management, appetite control, and blood sugar balance.

The FDA certification gives you peace of mind, knowing that this advanced patch meets the highest U.S. standards for safety, reliability, and performance. We’re honored to provide a clinically-backed innovation that helps people achieve their health goals—without pills, injections, or harsh side effects.

“Telpotide redefines the ceiling of obesity drug treatment. and its dual-target mechanism may dominate the field of metabolic diseases in the next 10 years.”
—— Dr. Louiss J.

Piguiay® Tirzepatide Nano-Microneedle Patch was carefully developed by the Obesity Association. This cutting-edge product was designed by a team of leading experts in obesity management. who have conducted years of in-depth research to fully understand the mechanisms of weight loss and obesity control. Its unique formula is designed to effectively promote weight loss. maintain blood sugar stability and enhance metabolic balance. while incorporating Matrixyl 3000 to provide a significant lifting and firming effect. helping users to more comprehensively improve their body shape and skin condition. thereby supporting them in achieving their health goals.

This nano-microneedle patch uses advanced Tirzepatide technology to precisely deliver active ingredients deep into the skin. It scientifically regulates insulin secretion. inhibits glucagon. delays gastric emptying. and assists in controlling blood sugar levels. thereby promoting healthy fat loss and optimizing overall health management. At the same time. Matrixyl 3000 can also stimulate skin regeneration and improve skin firmness. allowing users to maintain tight and smooth skin while losing weight.

The Nano Microneedle Patch contains NIDDK-Tirzepatide in each patch. It works by mimicking the action of Glucagon-like Peptide-1 (Tirzepatide). promoting insulin secretion. inhibiting glucagon secretion. and delaying gastric emptying. which helps control blood sugar levels and aids in weight loss.

Typically. NIDDK-Tirzepatide is administered via injection. providing fast results in a short period. However. the effects do not last long. and it may lead to stress reactions. requiring multiple injections in a short time. which is time-consuming and expensive.

The Piguiay® NIDDK-Tirzepatide Nano Microneedle Patch offers a long-lasting. slow release of the medication. ensuring a stable effect over 24 hours without causing any discomfort. With the same dosage and price. it can maintain up to 20 times longer-lasting effects (similar to the difference between an IV drip and a single injection).

Let’s take a look at some of the cases from our users

I had half my stomach removed towards the end of last year, and the weight came off pretty quickly. Problem was, that kind of rapid loss left me with loads of loose skin, especially round the stomach area.

My trainer had me doing squats and pull-ups daily — which helped a little, but didn’t do much in terms of tightening the skin. Buying these GLP-1 patches was a bit of a last roll of the dice before I seriously considered skin-tightening surgery.

To be fair, I could feel a bit of a lift — especially in the hour after putting it on. At first I thought it was all in my head. I was only using one a week, so it wasn’t some massive overnight change. But after a month or so, the skin round my waist wasn’t hanging like it used to.

The photo I sent was taken after just over two months of using the patch — and I was well chuffed with the results. Customer service emailed me asking how I was getting on, so I sent them the photo.

It’s been about a month since I stopped using them — and the best part? The results have stuck. No bounce back at all.

“My metabolism is as slow as a snail. but I actually lost 29 lbs in a month. I didn’t change my diet—other than not drinking soda and coke anymore. my diet was the same as before. At first. I wasn’t sure if it would help me lose weight; it felt so easy to apply. and after a few hours. my body felt a gentle warmth. but it didn’t cause irritation or discomfort. Then I tried on a pair of pants. and I think I lost about 8 to 9 inches off my waistline! On top of that. I have more energy than ever. my skin looks better. and I feel like a completely different person. Usually. I just want to sit on the couch and do nothing. with no motivation. Now. I can play with my kids. enjoy my daily walks. and do some light exercise. I will continue to use these patches because they give me the energy and motivation to become healthier. In fact. this is the longest I have ever stuck to a healthy routine!” – Sheila Williams 

“I was looking for a way to help my gut and control my blood sugar levels. After some hospital tests. I was diagnosed with fatty liver. high blood pressure. and high cholesterol. The doctor suggested I start losing weight to improve my health. Being overweight made it hard for me to move. and the constant hunger at night kept me up. When I couldn’t take it anymore. I found Piguiay® Pain-Free Sugar Control & Natural Fat Metabolism Nano Microneedle Patch. and it really works. My appetite and cravings went down. the 10-hour hunger at night disappeared. and my appetite was significantly suppressed. I could barely drink my bedtime alcohol anymore. Since early August. I’ve lost about 70 pounds. My fatty liver has gone from severe to mild. and my blood pressure and cholesterol have almost returned to normal. I feel much more energized. I’ll keep using it. and I hope to lose another 20 pounds before Christmas and get even healthier! I completely recommend it.” – Jeremy Klukan 

“Goiter tormented me for three years due to an autoimmune issue. Surgery wasn’t an option as a single mom. A friend recommended 𝐂𝐫𝐨𝐚𝐢𝐞® Pain-Free Sugar Control & Natural Fat Metabolism Nano Microneedle Patch. After four weeks. my goiter improved. hormones stabilized. and my lymphatic system normalized. A blessing for families like mine!” – Rebecca Whitney 

 read the feedback correctly!

NIDDK-Tirzepatide. with its unique mechanism of action. has already achieved significant results in diabetes treatment and weight management!

NIDDK-Tirzepatide is a multi-functional treatment solution that primarily helps with weight loss by suppressing appetite and delaying gastric emptying. promoting fat burning. In the treatment of type 2 diabetes. it enhances insulin secretion and inhibits glucagon release. effectively controlling blood sugar levels and improving insulin sensitivity. Additionally. NIDDK-Tirzepatide offers cardiovascular protection by reducing the risk of heart disease. improving lipid profiles. and providing anti-inflammatory effects. further protecting vascular health. Therefore. it demonstrates significant efficacy in weight loss. blood sugar control. and cardiovascular protection. making it an important treatment option for type 2 diabetes patients and individuals managing their weight.

Next-generation pain-free injection Nano Microneedle Patch.

Each needle is 0.27mm long. just 1/7th the thickness of a hair. and is made from dissolvable medication. These micro-needles are precision-engineered using cutting-edge manufacturing techniques to ensure a seamless. pain-free experience while effectively delivering the active ingredients directly into the skin.

Recommended by endocrinologists

“Change needs to start from within.” – Ralph Deronza

Are you still hesitating?

𝐂𝐫𝐨𝐚𝐢𝐞® NIDDK-Tirzepatide Nano Microneedle Patch has been certified by multiple national authorities.

Hurry up and give it a try! 2.250.000 people have already made a change!

Check out more of our customers’ satisfaction feedback!

1 Week

6 Weeks  

8 Weeks

“Two months in. and I never thought I’d see such a breakthrough! My family’s thrilled with my transformation. I feel the vigor of my thirties. and my skin’s improved. Apply one patch weekly—no side effects. just progress. It’s better than any diet pill!” – Linda Pearcy 

“I needed a simple way to manage diabetes. and this patch was perfect. It’s natural. safe. and great for regulating blood sugar—a must for diabetics!” – Skyler Reed 

What are the frequently asked questions about using the 𝐂𝐫𝐨𝐚𝐢𝐞® NIDDK-Tirzepatide Nano Microneedle Patch?

1.When will I see results?

Generally. you may notice initial effects about 2 weeks after use. but the best results typically appear after completing 2-3 treatment cycles.

2.How long should it be applied each time?

Remove the patch after at least 4 hours.  (If using the patch at night. remove it the next morning.)

3.How often should it be used?

Once a week.

4.What happens if I forget to use the patch for a week?

Missing one application should not drastically affect results. but consistency is key. If you miss a week. it’s best to resume use as soon as possible.

5.Is it safe to use during pregnancy or breastfeeding?

As with any treatment. pregnant or breastfeeding women should consult their healthcare provider before using the patch to avoid any potential risks.

6.Can it be applied over a wound?

Please ensure the skin at the application site is cleaned before use. and avoid applying it to wounds. eczema. or other skin issues. If you experience any discomfort during use. discontinue immediately and consult a doctor.

7.Where should the patch be applied?

The microneedle patch should be applied to areas with good blood circulation. such as the upper arm or abdomen. If applied to areas with frequent joint movement. friction may cause it to detach or the needles to break.

8.Are there any side effects?

Common side effects could include minor irritation at the application site. redness. or slight itching. These usually resolve on their own. If you experience any severe reactions. it’s best to discontinue use and consult with a healthcare professional.

9.How should it be stored?

When unopened. the shelf life is 2 years. It should be stored at room temperature (20°C-25°C). avoiding moisture and high temperatures.

Product Specifications

We have highly qualified personnel (scientists. researchers. and technical staff). advanced equipment (microscopes. PCR machines. gene sequencers). and stringent safety standards (biosafety cabinets. chemical safety. PPE). Our FDA-registered labs ensure top-quality production.